Abstract

AKR or C3H/HeJ transplanted mouse lymphomas, originally induced by Gross virus, could be neutralized by in vitro incubation with an immunosuppressive rabbit anti-mouse thymus cell serum. Neutralization was measured by significantly increased latent periods or decreased incidence (at a minimum of 90 days post-transfer) of lymphoma in syngeneic recipients of lymphoma cells incubated with antithymocytic serum when compared with syngeneic recipients of lymphoma cells incubated with normal rabbit serum.

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