Abstract
INTRODUCTION Fibrinolytic activity was studied in eight patients with Behcet’s syndrome (BS) and some of their relati ves. It was observed that all patients had decreased plasma fibrinolytic activity (DPFA) independently of disorders involving coagulation troubles, like thrombophlebitis. It was also observed that relatives who had in their past, history of recurrent oral ulcers, althought not exhibiting a typical clinical picture of BS, presented a DPFA. Based on the afore mentioned facts we can admit that DPFA may probably be a deter minant or codeterminant factor in the pathogenesis of the vasculitis lesions, instead of its consequence. Besides, we can not exclude the possible role of genetic factors, but further studies are needed to establish this.
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