Abstract
Incubation of the suspension of neutrophils in hypomagnetic field generated by a system of magnetic shields (residual constant magnetic field not exceeding 20 nT) leads to significant decrease in reactive oxygen species (ROS) production compared to control (geomagnetic field 44 μT), which was recorded by lucigenin-dependent chemiluminescence and fluorescent spectroscopy with 2,7-dichlorodihydrofluorescein diacetate (H2DCF-DA). During increase of constant magnetic field (CMF) in 0.02-44 μT range, polyextreme character of the response of the neutrophils to this action was observed: the minima of ROS production were at 0.02 μT and 7.0 μT, alternating with 2.5 μT and 30 μT values, at which the used test system does not react to the exposure to CMF.
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