Abstract
A fall of blood concentration of ketone bodies and free fatty acids as observed in rats and the involvement of endogenous insulin therein were examined. Hypoketonemia caused by glucose load was concluded to be solely dependent on the endogenous insulin activity, in view of the fact that extirpation of the pancreas as well as induction of alloxandiabetes or neutralization of endogenous insulin by anti-insulin serum completely abolished the hypoketonemia. In contrast, the decrease of blood concentration of free fatty acids in rats was at least partly due to a factor other than endogenous insulin activity, since a significant decline of blood level of free fatty acids was observed even in the totally pancreatectomized rats. The difference of ketonemic action between endogenous and exogenous insulin, as well as its dependence on other endocrine factors, is discussed. (Endocrinology 76: 910, 1965)
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
