Decoration of β-CD on Fe3O4@Ag core–shell nanoparticles as a new magnetically recoverable and reusable catalyst for the synthesis of 3,4-dihydropyrimidinones and 2,4-dihydropyrano[2,3-c]pyrazoles in H2O

Abstract

This report provides a description of the preparation and characterization of a Fe3O4@Ag-β-CD composite as a new magnetically recoverable catalyst for the synthesis of a number of biologically and pharmaceutically significant organic compounds in aqueous medium. The magnetic composite was characterized by TEM, EDS, XRD, VSM and FT-IR techniques. The result of the TEM analysis shows that the average size of Fe3O4@Ag-β-CD is less than 30 nm. Application of this hybrid material, as a catalyst, was studied efficiently in the one-pot multicomponent synthesis of 3,4-dihydropyrimidinone and 2,4-dihydropyrano[2,3-c]pyrazole derivatives. The main advantages of our method are simple isolation of products, easy recovery of the magnetic catalyst by an external magnet, reusability of the catalyst, and use of water as a green solvent.