Abstract
Objective: The purpose of this study was to investigate the anthelmintic activity of pomegranate (Punica granatum L.) peel decoction against Taenia saginata.
 Methods: The in vitro assay was conducted by observing the motility of T. saginata, which is isolated from cattle’s gastrointestinal tract, in various concentrations of pomegranate peel decoction with albendazole as a positive control.
 Results: The results showed that the anthelmintic activity was dependent on decoction concentration and the duration of contact between decoction and nematode. Decoction at moderate concentration causes paralysis, while high concentration causes death. The 75% and 100% pomegranate peel decoction started to cause death at 240 min and 150 min after contact with T. saginata.
 Conclusion: It was concluded that pomegranate peel decoction has anthelmintic activity.
Highlights
Human helminthic infections affect a large proportion of the world’s population
This method was applied to investigate the anthelmintic activity of pomegranate peel decoction against T. saginata, which is isolated from the cattle’s gastrointestinal tract
T. saginata was placed in a petri dish containing 10 ml of sterile saline, 0.4% albendazole, pomegranate peel decoction at various concentrations (25, 50, 75, and 100%)
Summary
Human helminthic infections affect a large proportion of the world’s population. In developing countries, they contribute to the prevalence of anaemia, malnutrition, eosinophilia and pneumonia [1]. They contribute to the prevalence of anaemia, malnutrition, eosinophilia and pneumonia [1] These infections, mainly due to lymphatic filariasis, soil-transmitted helminths, and schistosomiasis. It belongs to the class of neglected tropical diseases and are major targets of global elimination programs [2]. In 1982, there was the first approved anthelmintic for use in humans, i.e. albendazole (methyl N-(6-propylsulfanyl-1H-benzimidazol-2-yl) carbamate) [3, 4]. Albendazole is contraindicated for pregnant women and exhibited embryo toxicity in animals [4]
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