Abstract
Diabetes mellitus is a disease marked by an increase in blood sugar levels. At present many sufferers of Diabetes Mellitus whose blood sugar levels are not controlled so that it can cause complications. The purpose of this study was to reduce blood sugar levels with black onion extract and binahong leaf extract on mice (mus musculus). This study uses a Quasy Experimental design with One Group pre-posttest. Samples were taken A total of 32 mice consisted of 16 in the intervention group and the comparison intervention group. The independent variables in this study were black onion extract and binahong leaf extract, while the dependent variable was the blood sugar level of mice. Data were collected by observation sheets and analyzed using Kolmogorov-Smirnov and Independent sample T-tests. The results of this study showed that the difference between pre and post-reduction of black onion extract was 66.4 mg/dl and the difference between pre and post administration of binahong leaf extract was 66.2 mg/dl. While the analysis shows the value of p = value 0.985. The results of this study indicate that extracts of black garlic and binahong leaves are equally effective in reducing blood sugar levels and that there are no significant differences in reducing blood sugar levels in mice. Thus both the black onion extract and the binahong leaf are equally effective in reducing blood sugar levels.
Highlights
Changes in lifestyle and socio-economics due to urbanization and modernization, especially in large cities in Indonesia, are the cause of the increasing prevalence of degenerative diseases and are thought to be the main cause of death in Indonesia
This study aims to determine the decrease in blood sugar levels in the group by giving black onion extract and binahong leaf extract on mice (Mus Musculus)
Statistical test results using the Independent sample t-test in the comparison of the two groups seen from a decrease in blood sugar levels showed ρ = 0.985, with a significance level of 0.05 ρ = 0.985> α 0.05
Summary
Changes in lifestyle and socio-economics due to urbanization and modernization, especially in large cities in Indonesia, are the cause of the increasing prevalence of degenerative diseases and are thought to be the main cause of death in Indonesia. The prevalence of diabetes mellitus is expected to increase every year. According to the World Health Organization (WHO, 2017) states that the incidence of diabetes mellitus was 108 million in 1980 to 422 million in 2014. In 2015 diabetes mellitus was the 6th deadliest disease in the world with 1.6 million people each year in the past 15 years. Indonesia is ranked 7th in the world at 10.0 million people, where China ranked first with 109.6 million DM sufferers [2]. According to the Basic Health Research Report [3], the incidence of DM in East Java is 6.8% and ranks ninth of all provinces in Indonesia. The prevalence of diabetes in Indonesia is occupied by the province of East Java because diabetes is the top 10 most diseases. The number of DM patients according to Riskesdas has increased from 2007 to 2013 by 330,512 patients [4]
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