Abstract
Abstract The stability of vesicular stomatitis virus (VSV) messenger RNA during infection of Chinese hamster ovary (CHO) cells was investigated using the temperature-sensitive mutant, tsG114. By incubating infected cells at the nonpermissive temperature (39°), RNA synthesis was blocked and VSV mRNA decayed rapidly, as determined by sucrose density gradient analysis. Each of the five VSV mRNAs was also found to decay functionally at approximately the same rate suggesting that the differential rates of accumulation of VSV mRNAs observed in vivo are due to differential rates of transcription of specific VSV genes.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
