Deaths related to antipsychotics associated with higher doses

Abstract

For children aged 5–17 years, 100 mg or less of chlorpromazine equivalents was not associated with increased risk of death, but for doses greater than 100 mg, young adults aged 18–24 years had significantly increased risk of death, according to a study published online November 29, 2023 in JAMA Psychiatry. The conclusion — that mortality from antipsychotic medications is related to the dose — applies to children as well as young adults — the researchers said.