Abstract

Deadly High Altitude Pulmonary Disorders: Acute Mountain Sickness (AMS); High Altitude Pulmonary Edema (HAPE) and High Altitude Cerebral Edema (HACE): A Clinical Review

Highlights

  • Introduction and Facts Regarding AMSHow are the Symptoms of AMS Recognized?The mildest form of altitude sickness is Acute Mountain Sickness (AMS)

  • Acute Mountain Sickness is sometimes colloquially referred to as altitude sickness or mountain sickness; in South America it is called Soroche, in China it is called Jíxìng Gāoyuán Bìng and in Nepal it is called Tīvra Pahāḍa Rōga

  • Acetazolamide is a carbonic anhydrase inhibitor that is used for the medical treatment of glaucoma, epileptic seizures, idiopathic intracranial hypertension, altitude sickness, cystinuria, periodic paralysis, central sleep apnea and dural ectasia.There is good evidence that acetazolamide reduces symptoms of AMS in trekkers and mountaineers, it may have some unusual side-effects such as causing the extremities to tingle or food, especially fluids, taste strange

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Summary

Introduction and Facts Regarding AMS

The mildest form of altitude sickness is Acute Mountain Sickness (AMS). Where and how does acute mountain sickness happen? Most people in “relatively” good physical condition, remain feeling well up to altitudes of about 2500meters (8200 feet), the equivalent barometric pressure to which most modern airplane cabins are normally pressurized. Mild altitude sickness is called acute mountain sickness (AMS) and is quite similar to a hangover - it causes headache, nausea and fatigue This is very common: some people are only slightly affected, others feel very sick. Acetazolamide is a carbonic anhydrase inhibitor that is used for the medical treatment of glaucoma, epileptic seizures, idiopathic intracranial hypertension, altitude sickness, cystinuria (a rare condition in which stones made from an amino acid called cysteine form in the kidney, ureter, and bladder), periodic paralysis, central sleep apnea and dural ectasia (a widening of the dural sac surrounding the spinal cord).There is good evidence that acetazolamide reduces symptoms of AMS in trekkers and mountaineers, it may have some unusual side-effects such as causing the extremities to tingle or food, especially fluids, taste strange. The reason we relate our personal trek into veryhigh altitudes is because neither one of us suffered from any kind of AMS, one of us is past 40 and the other is in her 20’s! If you just fly in, you miss the beauty of the countryside, the incredible people of Nepal, their hospitality and their incredible love of life and nature and you are at a very high risk of AMS!!

Introduction
Introduction and Facts Regarding HACE
Findings
Quick Summary and Conclusion
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