De novo Ovarian Squamous Cell Carcinoma. A Case Report and Review of Literature

Abstract

Malignant ovarian tumours comprise of a spectrum of clinicopathologic entities. Many have comparable presenting clinical features, some are associated with unique and intriguing histomorphological features. Not only does a histopathology define a tumour’s ontogeny and biology, they may also predict prognosis and help plan an adjuvant therapy. What follows is a 17th case report of an exceedingly rare primary ovarian tumour (pure, de novo), squamous cell carcinoma (SCC). However, it is known that 2 % of mature teratomas harbour malignant component and up to 80 % will be squamous. Some pure SCCs will arise in association with a foci of endometriosis and very rarely entirely de novo [1–4]. SCC of ovary are aggressive tumours, which may be amenable to multimodality treatment. Due to conflicting evidence from literature, the best therapeutic option cannot be deciphered. Treatment needs to be tailored to patient profile.