De Novo Femoropopliteal stenoses: Endovascular Gamma Irradiation Following Angioplasty-Angiographic and Clinical Follow-up in a Prospective Randomized Controlled Trial

Abstract

The authors studied the results of a randomized controlled trial in which patients who underwent percutaneous transluminal angioplasty either received centered endovascular gamma irradiation or were in a control group. Patients were evaluated at various time-points with intra-arterial angiography, duplex ultrasonography, treadmill tests, and were also interviewed and the results were analyzed. At baseline the two groups had similar characteristics. The rates of target lesion restenosis at 6 and 12 months were significantly lower in the irradiation group. The authors concluded that patients who had endovascular irradiation after angioplasty of de novo femoropopliteal stenosis had a significantly reduced degree of stenosis at 6 and 12. Target vessel retreatment was more frequent in the irradiation group.