Abstract
This study from the Netherlands aimed to determine the utility of D-dimer testing in patients with impaired renal function. Because renal impairment is associated with elevated D-dimer concentrations, the specificity of D-dimer testing in patients with suspected pulmonary embolism (PE) and impaired renal function is reduced. Additionally, computed tomography (CT) scanning in patients with impaired renal function is relatively contraindicated given the possibility of worsening renal function from contrast nephropathy.
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