Abstract
The purpose of this study was to clarify the day-to-day variations of salivary cortisol to discuss the appropriate timing for collecting saliva in a day for stress evaluation. Saliva samples from twelve healthy adults were collected by means of Salivette(®) (SARSTEDT Co.) three times per day, immediately after awakening (Time1), 6:00 PM (Time2) and 30 min before going to bed (Time3), on 5 nonconsecutive days. Cortisol concentration was measured using a radioimmunoassay. Salivary cortisol concentration showed the larger value at Time1 than that at Time2. The mean value of %CV for day-to-day variation showed the smallest value at Time1 (mean: 43.1%) and the largest value at Time3 (mean: 100.3%). There were significant differences in %CV value between Time1 and Time3, Time2 (mean: 64.1%) and Time3. There are considerable day-to-day variations in salivary cortisol concentration measurements. From the viewpoint of day-to-day variation, collecting saliva immediately after awakening in the morning is thought to be more advantageous for evaluating cortisol concentration.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.