Abstract

BackgroundThe growth of geolocated data has opened the door to a wealth of new research opportunities in the health fields. One avenue of particular interest is the relationship between the spaces where people spend time and their health outcomes. This research model typically intersects individual data collected on a specific cohort with publicly available socioeconomic or environmental aggregate data. In spatial terms: individuals are represented as points on map at a particular time, and context is represented as polygons containing aggregated or modeled data from sampled observations. Uncertainty abounds in these kinds of complex representations.MethodsWe present four sensitivity analysis approaches that interrogate the stability of spatial and temporal relationships between point and polygon data. Positional accuracy assesses the significance of assigning the point to the correct polygon. Neighborhood size investigates how the size of the context assumed to be relevant impacts observed results. Life course considers the impact of variation in contextual effects over time. Time of day recognizes that most people occupy different spaces throughout the day, and that exposure is not simply a function residential location. We use eight years of point data from a longitudinal study of children living in rural Pennsylvania and North Carolina and eight years of air pollution and population data presented at 0.5 mile (0.805 km) grid cells. We first identify the challenges faced for research attempting to match individual outcomes to contextual effects, then present methods for estimating the effect this uncertainty could introduce into an analysis and finally contextualize these measures as part of a larger framework on uncertainty analysis.ResultsSpatial and temporal uncertainty is highly variable across the children within our cohort and the population in general. For our test datasets, we find greater uncertainty over the life course than in positional accuracy and neighborhood size. Time of day uncertainty is relatively low for these children.ConclusionsSpatial and temporal uncertainty should be considered for each individual in a study since the magnitude can vary considerably across observations. The underlying assumptions driving the source data play an important role in the level of measured uncertainty.

Highlights

  • The growth of geolocated data has opened the door to a wealth of new research opportunities in the health fields

  • Since a significant portion of administrative data is reported based on place of residence, what impacts might changing context over the day introduce into our understanding of exposure? Our efforts in each of these cases are focused on introducing the mechanisms through which a specific type of spatio-temporal uncertainty can enter an analysis and offering a tool to quantify the magnitude of this uncertainty

  • These tools are not intended to replace more precise attributions of contextual effects to individuals, but to provide opportunities for sensitivity analysis when more precise measurement is not feasible. We study these issues by intersecting two longitudinal and georeferenced datasets: the Family Life Project’s (FLP) point data on a specific cohort of children and the US Environmental Protection Agency’s (EPA) RiskScreening Environmental Indicators (RSEI) model that provides area data on air toxicity

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Summary

Introduction

The growth of geolocated data has opened the door to a wealth of new research opportunities in the health fields. One avenue of particular interest is the relationship between the spaces where people spend time and their health outcomes. In spatial terms: individuals are represented as points on map at a particular time, and context is represented as polygons containing aggregated or modeled data from sampled observations. Uncertainty abounds in these kinds of complex representations. Complicating matters is that context can be both generalizable and idiosyncratic in terms of contributing to the health outcomes of people whose lives intersect with a particular space at a particular time. Locations with high particulate matter (PM) are broadly harmful, especially to people who spend considerable time outdoors or are at elevated risk to PM. The 2014 Flint, Michigan water crisis was the result of public policy, changes in water sources, and aging infrastructure, among other factors; not the presence of lead pipes

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