Abstract
The clomiphene citrate challenge test (CCCT), in which serum FSH is measured before (day 3) and after (day 10) administration of clomiphene citrate (CC), is used as a test of ovarian reserve in infertile women. Estradiol (E2) is often measured on day 3 but is rarely checked on day 10 despite the fact that the change in E2 reflects ovarian responsiveness and follicular growth in response to CC. The only previous study to explore the prognostic value of E2 found no correlation between day 10 levels and response to gonadotropins (Scott et al., 1993).
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