Abstract

David S. Miller was Acting Scientific Director of the Division of Intramural Research at the National Institute of Environmental Health Sciences, National Institutes of Health, and Head of the Intracellular Regulation Group in the Laboratory of Toxicology and Pharmacology before he retired in 2016. David received his Ph.D. in biochemistry from the University of Maine in 1973. David was a Group Leader at the Michigan Cancer Foundation before joining the NIEHS in 1985. His research covered a wide range from renal excretory transport mechanisms to regulation of transporters at the blood–CSF and blood–brain barriers, from fish, amphibians and birds to mammals. David was an outstanding scientist with irresistible enthusiasm for science and an incredible ability to think outside the box while being an exceptional mentor and friend.

Highlights

  • In 1985, David was recruited to the National Institute of Environmental Health Sciences (NIEHS), National Institutes of Health (NIH) as an Expert Research Physiologist in the Laboratory of Cellular and Molecular Pharmacology

  • Scientific career—from chickens to regulatory pathways at the blood–brain barrier Postdoctoral work until mid‐1990s Early post‐doctoral and research scientist years at the Mount Desert Island Biological Laboratory Notes from Larry Renfro: David joined the Kinter laboratory at MDIBL in 1973 as a postdoc, the year before I moved to the University of Connecticut, but that overlap was sufficient to cement a career long respect for and interaction with him [5,6,7,8,9]

  • We found that Mrp2 is present at the apical membrane of human breast ductules suggesting that Mrp2 transports carcinogens into the lumens of these ductules

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Summary

Introduction

Scientific career—from chickens to regulatory pathways at the blood–brain barrier Postdoctoral work until mid‐1990s Early post‐doctoral and research scientist years at the Mount Desert Island Biological Laboratory Notes from Larry Renfro: David joined the Kinter laboratory at MDIBL in 1973 as a postdoc, the year before I moved to the University of Connecticut, but that overlap was sufficient to cement a career long respect for and interaction with him [5,6,7,8,9]. The 1990s to The Millennium: head of the Intracellular Regulation Group at NIEHS Studying renal organic anion and cation uptake Notes from Rosalinde Masereeuw and Gert Fricker: In the 1990s, David’s research was focused on transport processes in the kidney, and he was one of the first researchers combining functional and mechanistic aspects of transport processes in intact kidney tubules [26, 37].

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