Abstract

The four serotypes of dengue virus (DENV1-4) are the causal agents of the emerging disease Dengue Fever and its severe forms. DENV is inoculated into human blood through a mosquito bite. Thus, plasma is an important media for DENV dissemination in infected persons and several important interactions should take place for the virus with human plasma proteins that strongly influence or may determine the course of the infection. This dataset contains 239 proteins identified in the elution fractions of human plasma subjected to DE-52 anion exchange chromatography. Data on DENV2 infection of Huh 7.5 cells in presence of the human plasma fraction is also presented.

Highlights

  • Dataset on protein composition of a human plasma sub-proteome able to modulate the Dengue 2 virus infection in Huh 7.5 cells

  • Plasma is an important media for DENV dissemination in infected persons and several important interactions should take place for the virus with human plasma proteins that strongly influence or may determine the course of the infection

  • This dataset contains 239 proteins identified in the elution fractions of human plasma subjected to DE-52 anion exchange chromatography

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Summary

Specifications table

DOI of original article: http://dx.doi.org/10.1016/j.jprot.2015.11.003 n Corresponding author. http://dx.doi.org/10.1016/j.dib.2015.12.016 2352-3409/& 2015 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

Data accessibility
Value of the data
Viruses and cell lines
Fractionation of human plasma samples
Virus-binding activity of plasma fractions
Protein composition of AXC eluates
DENV2 infection in presence of ELUAXC
Findings
Toxicity assay

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