Data_Sheet_1.xlsx

Abstract

Objectives To analyze the clinical and imaging features of acute ischemic stroke (AIS) related to gastrointestinal malignant tumor, and to explore the prognostic factors. Methods Clinical data of consecutive patients with gastrointestinal malignant tumor complicated with AIS admitted to the Department of Neurology and Oncology in Lanzhou University Second Hospital from April 2015 to April 2019 were retrospectively analyzed. Patients were divided into good prognosis (mRS 0-2) and poor prognosis (mRS >2) based on 90-day mRS score after discharge. Multivariate logistic regression model was used to analyze the prognostic factors. Results A total of 68 patients were enrolled with an average age of 61.78±6.65 years, including 49 males (72.06%). There were 18 patients in good prognosis group and 50 patients in poor prognosis group. Univariate analysis showed that Hcy, D-dimer, Thrombin‐antithronbin complex (TAT) and Three Territory Sign in magnetic resonance imaging (MRI) were risk factors for poor prognosis. Multivariate analysis showed that increased D-dimer (OR 4.497, 95%CI 1.014-19.938) and TAT levels (OR 4.294, 95%CI 1.654-11.149) were independent risk factors for the prognosis in such patients. Conclusion Image of patients with gastrointestinal malignant tumor-related AIS is characterized by Three Territory Sign (multiple lesions in different vascular supply areas). Increased TAT and D-dimer levels are independent prognostic risk factors. TAT is more sensitive to predict prognosis than D-dimer.