Data on the effects of low iron diet on serum lipid profile in HCV transgenic mouse model

Alice Conigliaro,Viviana Costa,Rosario Amato,Carmine Mancone

doi:10.1016/j.dib.2017.03.020

Alice Conigliaro, Viviana Costa + Show 2 more

Open Access

https://doi.org/10.1016/j.dib.2017.03.020

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Abstract

Here, we presented new original data on the effects of iron depletion on the circulating lipid profile in B6HCV mice, a murine model of HCV-related dyslipidemia. Male adult B6HCV mice were subjected to non-invasive iron depletion by low iron diet. Serum iron concentration was assessed for evaluating the effects of the dietary iron depletion. Concentrations of circulating triglycerides, total cholesterol, Low Density Lipoproteins (LDLs), High Density Lipoproteins (HDLs) were analyzed and reported by using stacked line charts. The present data indicated that low serum iron concentration is associated to i) lower serum triglycerides concentrations and ii) increased circulating LDLs. The presented original data have not been published elsewhere.

Highlights

Data on the effects of low iron diet on serum lipid profile in HCV transgenic mouse model
Male adult B6HCV mice were subjected to non-invasive iron depletion by low iron diet
Raw, Analyzed B6HCV transgenic mice were from Markus Heim laboratory at Department of Biomedicine University Hospital of Basel Iron and lipids concentrations were measured in serum samples of B6HCV mice fed low iron diet for thirty days

Summary

Introduction

Data on the effects of low iron diet on serum lipid profile in HCV transgenic mouse model. We presented new original data on the effects of iron depletion on the circulating lipid profile in B6HCV mice, a murine model of HCV-related dyslipidemia. Male adult B6HCV mice were subjected to non-invasive iron depletion by low iron diet.

Results

Conclusion