Abstract
Cytopiloyne (CP), a novel polyacetylene compound extracted from B. pilosa, shows a multi-bioactivity, including immunomodulatory and antidiabetes. Here, we investigated the anti-Listeria effect of cytopiloyne in mice by assessing mortality, clearance of L. monocytogenes, and pathology examination. The data presented herein are supplemental to our research article entitled “Cytopiloyne, a polyacetylenic glucoside from Bidens pilosa, acts as a novel anticandidial agent via regulation of macrophages” [1].
Highlights
Cytopiloyne (CP), a novel polyacetylene compound extracted from B. pilosa, shows a multi-bioactivity, including immunomodulatory and antidiabetes
Image Survival rate monitor, microscope, and serial dilution plate method Analyzed Control and Cytopiloyne intraperitoneal injections at various concentration Resistance of C57BL/6J mice to Listeria monocytogenes Taichung, Taiwan Data is within this article
May provide a new therapeutic strategy that uses a combination treatment of antimicrobial drugs and edible immunodulatory herbs to improve the efficacy of antimicrobial drug therapy on immunosuppressed patients
Summary
Data on the effect of Cytopiloyne against Listeria monocytogenes infection in mice Chih-Yao Chung a,1, Wen-Chin Yang b,c,d,e,1, Chih-Lung Liang f, Hsien-Yueh Liu a, Shih-Kai Lai a, Cicero Lee-Tian Chang a,n a Department of Veterinary Medicine, National Chung Hsing University, Taichung 402, Taiwan b Agricultural Biotechnology Research Center, Academia Sinica, Taipei 11529, Taiwan c Department of Aquaculture, National Taiwan Ocean University, Keelung 202, Taiwan d Institute of Pharmacology, Yang-Ming University, Taipei 112, Taiwan e Department of Life Sciences, National Chung-Hsing University, Taichung 402, Taiwan f Department of Microbiology and Immunology, Institute of Microbiology and Immunology, Chung Shan Medical University, Taichung 402, Taiwan article info. The data presented are supplemental to our research article entitled “Cytopiloyne, a polyacetylenic glucoside from Bidens pilosa, acts as a novel anticandidial agent via regulation of macrophages” [1].
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