Abstract
AbstractEffective data management is critical for quality research in any hematopoietic stem cell transplantation (HSCT) center for accuracy, reliability, and validity of the data. HSCT research is a dynamic and multi-domain process encompassing innovative therapeutic modalities, techniques, and interventions to change the existing standard of care and optimize survival outcomes and patients’ quality of life. Research has evolved as one of the core competencies for the standardization, accreditation, and academic standing of the transplant center. The Data Unit is the center of gravity and the hub of research (databases, registries, translational research, and randomized control trials) in a quality cancer care facility. HSCT data collection, collation, and interpretation have become an integral part of the treatment rather than an option. Quality assurance (QA) and continuous quality improvement (CQI) in data management are pivotal for credibility, measurable/quantifiable outcomes, clinically significant impact, and setting benchmarks. Quality assurance, ethical conduct, and monitoring of HSCT data are the hallmarks of a center of excellence in galvanizing the therapeutic interventions and optimizing the outcomes.
Highlights
Hematopoietic stem cell transplantation (HSCT) databases are the backbone of any quality transplant program to achieve desired end states as per the institutional lines of efforts
Databases and the consent formats need to be approved by the Institutional Review Boards (IRBs) as per the local rules and regulations and the Standard Operating Procedures (SOPs)
Data managers are required for quality data management and their continuing education and training, and interdisciplinary teamwork is critical for the optimum use and outcomes of the HSCT databases [6]
Summary
HSCT databases are the backbone of any quality transplant program to achieve desired end states as per the institutional lines of efforts.
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