Abstract

The data included in this article shows homologies of genes in porcine X-chromosome inactivation center, XIC, to each orthologue in human and mouse XIC. Open sequences of XIC-linked genes in human and mouse were compared to porcine genome and sequence homology of each orthologue to porcine genome was calculated. Sequence information of porcine genes encoded in the genomic regions having sequence homology with the human XIC-linked genes and their 2 Kb upstream regions were downloaded. Obtained information was used to design primer pairs for expression and methylation pattern analyses of XIC-linked genes in pigs. The data represented in here is related and applied to the research article entitled “Dosage compensation of X-chromosome inactivation center, XIC,-linked genes in porcine preimplantation embryos: Non-chromosome wide initiation of X-chromosome inactivation in blastocysts”, published in Mechanisms of Development Hwang et al., 2015 [1].

Highlights

  • Table, Figure, and Text file Download public sequence information of human and mouse genes encoded in X-chromosome inactivation center, XIC, to find homologue regions in porcine genome

  • Genomic and transcript sequences of the human and mouse genes encoded in genomic region ranging between CDX4 and RLIM, which were determined to be the XIC synteny in this study, were downloaded from GenBank and aligned to the pig genome using BLAST

  • The sequence homology rate of each blast hit (B) from alignment of one query was calculated by magnifying the sequence identity between blast hits and their searched counterpart region in pig: Homology rate of individual blast hitðBÞ 1⁄4 Qurey coverage of blast hitðAÞ Â Identity

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Summary

Specifications Table

Data format Experimental factors Experimental features Data source location Data accessibility.

Value of the data
Sequence homology of human and mouse XIC-linked genes to pig genome
Primer pairs detecting porcine XIC-linked genes
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