Abstract
CIGB-552 is a second generation antitumor peptide that displays potent cytotoxicity in lung and colon cancer cells. The nuclear subproteome of HT-29 colon adenocarcinoma cells treated with CIGB-552 peptide was identified and analyzed [1]. This data article provides supporting evidence for the above analysis.
Highlights
Experimental factors Isolation of the Nuclear Proteins Enriched Fraction, trypsin digestion and isotope labeling of peptides
The data details the dual-fractionation by polyacrylamide gel electrophoresis (DF-PAGE) separation method used in the proteomics analysis of GIGB-552 peptide effect
The data provides an overview of the nuclear proteins differentially modulated in HT-29 colon adenocarcinoma cells treated with the antitumor peptide CIGB-552 and their functional classification
Summary
Teresa Núñez de Villavicencio-Díaz a, Yassel Ramos Gómez a, Brizaida Oliva Argüelles b, Julio R. Article history: Received 11 June 2015 Received in revised form June 2015 Accepted June 2015 Available online 8 July 2015. CIGB-552 is a second generation antitumor peptide that displays potent cytotoxicity in lung and colon cancer cells. The nuclear subproteome of HT-29 colon adenocarcinoma cells treated with CIGB-552 peptide was identified and analyzed [1]. This data article provides supporting evidence for the above analysis.
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