Abstract
Intraoperative LDR prostate brachytherapy requires the availability of a sufficient number of radioactive seeds of appropriate activity to deliver the prescription dose to a given target volume. This number can be estimated with a volume study, but that is inconvenient for patients who travel for the procedure and a strain on clinical resources. Instead, we order seeds based on a diagnostic MRI that often is taken months before the procedure. To make up for the volume estimate uncertainty, an excess of seeds is ordered, resulting in radioactive waste and higher cost. In this work, we describe a knowledge-based system for seed ordering that ensures having enough seeds for all cases, without the use of a volume study while minimizing waste seeds.
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