Abstract
Synthesis of „Chiral”︁ α‐Aminoisobutyric Acidα‐Methylalanine (α‐aminoisobutyric acid), a rare naturally occuring achiral amino acid, is an efficient inducer of secondary structure for peptides and easy to characterize by NMR because of its prochiral methyl groups. „Chiral”︁ α‐methylalanine is enantioselectively synthesized via the bislactim‐ether method where the pro‐R‐methyl group has three or one deuterium atom(s).
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