Abstract

Background. The use of prostate-specific antigen test has markedly increased in Danish general practice in the last decade. Despite the national guidelines advice against PSA screening, opportunistic screening is supposed to be the primary reason for this increased number of PSA tests performed. Aims. Based on the increase in the amount of PSA conducted, we aimed to analyse how GPs in Denmark use the PSA test. Methods. A self-administrated questionnaire concerning symptomatic and asymptomatic patient cases was developed based on the national and international guidelines and the extensive literature review, and an in-depth interview conducted with a GP was performed. Results. None of the GPs would do a PSA measurement for an asymptomatic 76-year-old man. For asymptomatic 55- and 42-year-old men, respectively, 21.9% and 18.6% of GPs would measure PSA. Patient request and concern could be potential reasons for measuring PSA for asymptomatic patients. Almost all GPs stated that a PSA measurement is indicated for symptomatic 49- and 78-year-old men, respectively, 98.9% and 93.8%. Conclusion. Opportunistic PC screening is being performed in general practice to a high degree. Hence, current guidelines are not followed, and intense focus should be on more effective implementation strategies in order to avoid overuse of PSA.

Highlights

  • Prostate cancer (PC) in Denmark (DK) and many other western countries is the most prevalent cancer in men

  • The asymptomatic case stories explore general practitioners (GPs) views on opportunistic screening, where age was suspected to be a significant factor for the relevance of a Prostate-specific antigen (PSA) measurement

  • It has been suggested that when an asymptomatic patient requests a PSA test, he should be informed about the possible consequences of a positive test [12]

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Summary

Introduction

Prostate cancer (PC) in Denmark (DK) and many other western countries is the most prevalent cancer in men. Prostate-specific antigen (PSA) testing used as opportunistic screening could be a reason for the increase in incidence [3, 4]. The use of prostate-specific antigen test has markedly increased in Danish general practice in the last decade. Despite the national guidelines advice against PSA screening, opportunistic screening is supposed to be the primary reason for this increased number of PSA tests performed. Based on the increase in the amount of PSA conducted, we aimed to analyse how GPs in Denmark use the PSA test. None of the GPs would do a PSA measurement for an asymptomatic 76-year-old man. For asymptomatic 55- and 42-year-old men, respectively, 21.9% and 18.6% of GPs would measure PSA. Almost all GPs stated that a PSA measurement is indicated for symptomatic 49- and 78-year-old men, respectively, 98.9% and 93.8%. Current guidelines are not followed, and intense focus should be on more effective implementation strategies in order to avoid overuse of PSA

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