Abstract
The concept of damage control resuscitation focuses on the reversing of the lethal trauma triad of coagulopathy, acidosis, and hypothermia in severe uncontrolled hemorrhage. Five key components of damage control resuscitation are permissive hypotension and restrictive fluid administration, hemostatic resuscitation, early hemorrhage control, correction of acidosis, and rewarming. Additional studies on the personalized resuscitations, such as individual blood product ratios, and targeting more accurately to those patients who can benefit most through additional high-quality prospective randomized intervention studies are needed.
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