Abstract
The aim of this observational study was to analyze the effect of a toothpaste with biomimetic zinc hydroxyapatite (HAP) on subjective parameters after a four-week home use. Patients with subjective dentin hypersensitivity were recruited at three dental practices in Germany and received a questionnaire with visual analogue scales and Likert scales both at baseline and follow-up. The questionnaire was specifically developed for this study and focused on questions about subjective parameters like dentin hypersensitivity, tooth surface texture, tooth color, and freshness after toothbrushing. Patients answered the questionnaire both at baseline and after a four-week home use (follow-up) of the HAP toothpaste. Data of 46 patients were analyzed by paired t-test and non-parametric Wilcoxon signed-rank test, respectively. Subjective parameters on dentin hypersensitivity were reduced after the four-week use of the HAP toothpaste (p < 0.001). Additionally, patients assessed their tooth surface as smoother (p < 0.001), tooth color as whiter (p = 0.003), and reported a stronger feeling of freshness after toothbrushing (p = 0.014) after four-week use of the HAP toothpaste compared to the previously used toothpaste. In conclusion, the tested toothpaste with biomimetic HAP is well-suited for individuals suffering from dentin hypersensitivity, because subjective symptoms on dentin hypersensitivity were reduced. Additionally, patients reported smoother and whiter teeth after using the HAP toothpaste.
Highlights
Toothpastes have been developed and continually improved for several decades to promote oral health [1]
(II) The HAP toothpaste has more positive effects on the parameters of dental care convenience, i.e., tooth surface structure, tooth color, gum bleeding, and feeling of freshness after toothbrushing than the toothpaste previously used by the patients
This study indicates that subjective dentin hypersensitivity in cold, sweet, and/or acidic conditions decreased significantly after using the HAP toothpaste compared to the previously used toothpaste
Summary
Toothpastes have been developed and continually improved for several decades to promote oral health [1]. The number of publications using biomimetic concepts, e.g., hydroxyapatite, in preventive oral care has increased in the last decade [7,10,11], starting with publications in the late 1980s, e.g., by Huettemann and Doenges [12] and Kani et al [13]. The aim of this observational study using a pre-post-design was to analyze possible changes of various subjective parameters after a four-week home use of a toothpaste with biomimetic HAP in patients suffering from dentin hypersensitivity using a specific questionnaire developed by the authors. (II) The HAP toothpaste has more positive effects on the parameters of dental care convenience, i.e., tooth surface structure, tooth color, gum bleeding, and feeling of freshness after toothbrushing than the toothpaste previously used by the patients (secondary hypothesis)
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