Abstract
The Dépistage Cognitif de Québec (DCQ) was developed by expert Behavioural Neurologists and Clinical Neuropsychologists based on updated criteria for Alzheimer's disease (AD), primary progressive aphasia (PPA) and behavioral variant frontotemporal dementia (FTD). It targets five cognitive domains: Memory, Visuospatial, Executive, Language and Behaviour. This study aimed to provide normative data for the DCQ and measure its psychometric properties. We recruited 400 healthy French-speaking Canadians aged between 50 and 90 years old. Subjects were excluded if they had cognitive complaints, a personal history of neurological or psychiatric disorder, untreated metabolic condition, disabling visual and hearing disorders or illiteracy. All participants completed both the DCQ (25–30 minutes) and the MoCA (10–15 minutes) in a random order, on the same day. Normative data were based on participants who scored ≥ 26 on the MoCA (n=250). A random sample of 45 participants was retested within 1–3 months of initial administration to examine test–retest reliability. Fifty questionnaires picked at random among the 400 participants were scored again by two blinded and independents raters to assess interrater reliability. Mean DCQ total score (out of 100) was 89.17 (SD=7.36). Pearson's correlation coefficient showed a strong and significant correlation (r=.71, p<. 001) with the Montreal Cognitive Assessment (MoCA). Internal consistency for the cognitive domains assessed by Cronbach's alpha was satisfactory (.74). Test-retest reliability was adequate (Pearson's coefficient =. 70, p<. 001) and interrater reliability, excellent (intraclass correlation=. 99, p<.001). Normative data shown in percentiles were stratified by age and education (See Table). This study suggests that the DCQ is a valid and reliable cognitive screening test. Application of the DCQ on populations with atypical dementias is underway to derive sensitivity and specificity values for various dementias.
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