Year-end Sale % OFF 
Abstract
Intraperitoneal gelatin sponge implants were used in guinea-pigs to examine the effect of D-penicillamine on the delayed hypersensitivity reaction in vivo. When it was administered daily in a dose of 200 mg/kg for 14 days before sensitisation or for 14 or 30 days before challenge, D-penicillamine increased the number of exudate cells during the onset of the delayed hypersensitivity reaction. About 20% more polymorphonuclear cells accumulated in the sponges within 6-12 hours of implantation than did without D-penicillamine. Moreover, mononuclear cells also increased up to 20%, but this effect was apparent only 24 to 72 hours after sponge implantation and if D-penicillamine had been administered immediately before challenge.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
