Abstract
In a 2 k -factorial experiment with limited resources, when practitioners can identify the non-negligible effects and interactions beforehand, it is common to run an experiment with a saturated design that ensures the unbiased estimation of the non-negligible parameters of interest. We propose a method for the construction of D-optimal saturated designs for the mean, the main effects, and the second-order interactions of one factor with the remaining factors. In the process, we show the problem is just as hard as the Hadamard determinant problem.
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