D-dimer relation with hypertension and non-hypertension in covid-19 patient

Abstract

Coronavirus disease 2019 (COVID-19) is an infectious disease caused by SARS-CoV-2. It mainly affects lungs, but it also affects other systems too including cardiovascular system. Apparently, comorbidity may exacerbate the COVID-19 symptoms. Hypertension is the most common comorbidities in COVID-19 patients. Some COVID-19 patients have increased their d-dimer level which is a test to detect coagulation. It is suspected that prolonged high blood pressure might cause inflammation in the endothel and release inflammatory markers. Thus, the blood viscosity might also increase. The purpose of this research is to understand the association between d-dimer with hypertension in patients with COVID-19 at Dr.Soetomo General Academic Hospital from March – June 2021. The study design of this research is retrospective cross-sectional model which use medical records of COVID-19 patients at Dr. Soetomo General Academic Hospital, Surabaya, Indonesia in March 2021-June 2021. From 86 data which fulfil inclusion criteria will be tested using Chi-square. Most COVID-19 patients were aged between 30-60 years (68.6%). Based on sex distribution, the majority of patient was male (54.7%). There were no significant differences of d-dimer level based on hypertension (p=0.890), age (p=0.494), and sex (0.305). There was no correlation between d-dimer and hypertension comorbidity.