Abstract
Rats were preoperatively trained on a 5-unit linear maze and were then subjected to fimbria lesions. The animals were then retested on the same task with one group of rats with fimbria lesions and a control group being injected daily with 0.5 mg/kg d-amphetamine sulfate prior to testing. Lesions significantly impaired postoperative performance of the task, while amphetamine facilitated performance in fimbria lesioned rats. Due to an optimal learning of the task, performance of control animals was not significantly facilitated. These results raise several important issues including the mechanisms of functional recovery after brain lesions and the role of the hippocampal formation in learning and memory.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
