Abstract
ABSTRACT Information accumulated over the past decades on the physiological functions and metabolic pathways of biosynthesis and degradation of D-amino acids has led to a renewed interest in their study. These isomers are known to form both in nature and during the chemical synthesis of L-amino acids for feeding and pharmacological purposes, as well as in the industrial processing of some raw materials. This article discusses the positive and negative effects of D-amino acids on the human body, animals and the environment. In addition, the scientific data concerning the mechanisms of cytotoxic action of D-amino acids and their industrial and biomedical potential are summarized.
Highlights
As components of peptides, peptide hormones, structural and immune proteins, are the most important bioregulators involved in all life processes along with nucleic acids, carbohydrates and lipids
Whereas L-amino acids in most cases have a positive effect on the body, D-amino acids may have adverse effects
Active peptides containing D-amino acids are found in the cells of higher eukaryotic organisms; the only difference is that they are primarily formed as a result of post-translational modification of a precursor consisting of L-amino acids
Summary
As components of peptides, peptide hormones, structural and immune proteins, are the most important bioregulators involved in all life processes along with nucleic acids, carbohydrates and lipids. Active peptides containing D-amino acids are found in the cells of higher eukaryotic organisms; the only difference is that they are primarily formed as a result of post-translational modification of a precursor consisting of L-amino acids.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
