Abstract
Introduction: The impurities of the air inside the buildings and the resulting adverse health effects have become an increasing problem. Typically indoor air impurities are mixtures of many chemica...
Highlights
The impurities of the air inside the buildings and the resulting adverse health effects have become an increasing problem
24 samples were tested in four different cell types using neutral red uptake and water-soluble tetrazolium salt 1 (WST-1) assays
We investigated whether the cytotoxicity of indoor air can be detected from water samples condensed from indoor air using conventional cytotoxicity/cell viability assays
Summary
The impurities of the air inside the buildings and the resulting adverse health effects have become an increasing problem. Indoor air samples from 75% sampling sites where people reported health symptoms caused adverse effects in THP-1 macrophage/WST-1 assay. Conclusions: The assessment of indoor air cytotoxicity using water samples condensed from the indoor air and THP-1 macrophage/WST-1 assay provides a novel and practical biological approach for investigating indoor air quality. This method does not replace existing methods, but supplements them and provides a fast and cheap alternative for the first-stage screening for recognizing poor indoor air regardless of its source. The impurities of the air inside the buildings and the resulting adverse effects on human health have become an increasing problem. Requirements for assessments of harmful nonvolatile substances, such as mold toxins, biocides, and tensides, are typically lacking
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