Abstract
Cytotoxicity of Soursop Leaves (Annona muricata) against Cervical HeLa Cancer Cells
Highlights
Cancer is the leading cause of 8.8 million death globally in 2015 and ranked as the 2nd disease with highest mortality.[1]
One of which is by utilizing natural sources available in Indonesia such as soursop (Annona muricata) leaves which has been used in folk medicine as a treatment for various diseases, including cancer
The results showed that three extracts of A.muricata have strong cytotoxicity against cervical Henrietta μl (HeLa) cells
Summary
Cancer is the leading cause of 8.8 million death globally in 2015 and ranked as the 2nd disease with highest mortality.[1]. Modalities of treatment available for cervical cancer consist of chemotherapy, radiation, nuclear therapy, and surgery based on stadium of the cancer. These treatments have several limitations due to serious side effects such as disrupting cell metabolism, nausea, vomitting, nephrotoxicity, anemia, ototoxicity. Current treatments available for cervical cancer are chemotherapy, radiation, surgery, and nuclear therapy. These treatments still have several limitations due to serious side effects, development of resistance, and very expensive price. Conclusion: A.muricata leaves extracts are potential to be developed as a novel alternative therapy for cervical cancer.
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