Abstract
Cytotoxic effects of tamoxifen in breast cancer cells
Highlights
Cancer is a common cause of death nationwide[1], with the number of new cases of cancer in the US was estimated to be ca. 1.7 million in 2016[2]
The cytotoxic effects of tamoxifen were measured in the MCF7 cell line using the Methylthiazol tetrazolium (MTT) method[26]
MCF7 cells were treated with various concentrations of tamoxifen (200, 100, 50, 25, 12.5, 6.25, 3.125, 1.5625, and 0.78125 μg/mL) for 24 h at 37 °C
Summary
Cancer is a common cause of death nationwide[1], with the number of new cases of cancer in the US was estimated to be ca. 1.7 million in 2016[2]. Cancer is a common cause of death nationwide[1], with the number of new cases of cancer in the US was estimated to be ca. The number of cancer deaths was estimated at more than www.jumdjournal.net. Chemotherapy, and surgery can be used to control tumor growth, but these options need to be effective to manage breast cancer metastases[9,10,11,12]. Protease enzymes such as caspases exhibit cysteine protease activity and play an important role in apoptosis or programmed cell death[13,14]
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