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Abstract
The toxicity of hexavalent chromium was tested on synchronous cultures of light-grownE. gracilis. Chromium was administered as K2Cr2O7 at concentrations ranging from 1.5 to 9.0 μg/ml. It induced a marked inhibition of cell proliferation, accompanied by a great increase in cell size. In addition, at the higher concentrations (4.5 to 9.0 μg/ml), chromium caused the appearance of globular or lobed giant cells. These cells probably resulted from an inhibition of cytokinesis, as demonstrated by multinucleation and the aspect of the pellicle, which showed incipient signs of replication.
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