Abstract
Multipurpose solutions (MPSs) used for soft contact lens care contain agents, which can produce alterations in the tear film and ocular surface, such as keratitis, dry eye or conjunctivitis [1,2] Currently, the objective in the contact lens industry is to create novel formulations of MPSs with new agents in order to improve the ocular heath, comfort and to avoid discontinuing contact lens wear [3-5].
Highlights
Five multipurpose achieved significant results (p
Our study further confirmed the results of previous reports the beneficial effect of Aloe Vera, because we have demonstrated that when Aloe Vera is added to MPS, at 1%, it is able to increase cellular viability of corneal epithelium over normal values (119.71 ± 6.74%)
We found two commercial multipurpose solutions with similar effect improving cellular viability than solutions enriched with Aloe Vera, MPS4 (Bio-True) and MPS8 (Pure Moist Opti-Free)
Summary
Multipurpose solutions (MPSs) used for soft contact lens care contain agents, which can produce alterations in the tear film and ocular surface, such as keratitis, dry eye or conjunctivitis [1,2] Currently, the objective in the contact lens industry is to create novel formulations of MPSs with new agents in order to improve the ocular heath, comfort and to avoid discontinuing contact lens wear [3,4,5]. The purpose of this study was to evaluate the cytotoxic effect in vitro of different commercial multipurpose solutions. We have compared them with a multipurpose solution enriched with different concentration of Aloe Vera, and we have followed their possible protector effect on corneal surface
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