Abstract
The data presented in this article are related to the research article entitled “14-deoxy-11,12-didehydroandrographolide induces DDIT3-dependent endoplasmic reticulum stress-mediated autophagy in T-47D breast carcinoma cells”, which the mechanistic toxicology properties of 14-deoxy-11,12-didehydroandrographolide (14-DDA) were investigated (Tan et al., 2016 [1]). This article describes the derivation of cytotoxic parameters of 14-DDA, cell viability data after double transfection and DDIT3 silencing in T-47D cells.
Highlights
Cytotoxic data of 14-deoxy-11, 12-didehydroandrographolide (14-DDA), double transfection and DDIT3 silencing data in T-47D breast carcinoma cells
The data presented in this article are related to the research article entitled “14-deoxy-11,12-didehydroandrographolide induces DDIT3dependent endoplasmic reticulum stress-mediated autophagy in T47D breast carcinoma cells”, which the mechanistic toxicology properties of 14-deoxy-11,12-didehydroandrographolide (14-DDA) were investigated (Tan et al, 2016 [1])
This article describes the derivation of cytotoxic parameters of 14-DDA, cell viability data after double transfection and DDIT3 silencing in T-47D cells. & 2016 The Authors
Summary
Figures Envision 2104 multilabel plate reader (Perkin Elmer, USA), CFX96TM Real-Time PCR Detection System (Bio-Rad Laboratories, USA), ChemiDocTM XRS Imaging System (Bio-Rad Laboratories, USA) and Quantity Ones 1-D Analysis Software (Bio-Rad Laboratories, USA). The data is beneficial to researchers who are interested in the pharmacology properties of diterpenoids and Andrographis paniculata Nees. This data set is beneficial to researchers who want to derive cytotoxic parameters of compounds in cell lines. The data is helpful to ensure silencing of both mRNA and protein expressions at suitable time points when cells are transfected with siRNA.
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