Abstract
The methanolic extract of the root wood of Michelia compressa (Maxim.) Sargent showed cytotoxicity against MCF-7, NCI-H460 and SF-268 cancer cell lines. Bioassay-guided fractionation of the chloroform-soluble layer led to the isolation of costunolide and liriodenine with cytotoxic activities, along with the isolation of twenty-seven known compounds. The active costunolide existed as major constituent in this study.
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