Abstract
<p>The pure compound relatively (85 mg) was isolated from 4.5 kg <em>Brucea javanica</em> (L.) Merr. fruits sample. It was obtained from ethyl acetate fraction as a red-brownish amorphous solid of melting point 202-206 <sup>o</sup>C. Phytochemical screening of isolate showed positive result of terpenoid group. Based on analysis by UV, IR,<sup>1</sup>H-NMR and <sup>13</sup>C-NMR spectroscopy and by comparison with known related compounds, indicated that isolate is quassinoid compound named Picras 3- en- 21- oat acid, 15-(acetyloxy)-13,20- epoxy-3-(ß-D- glucopyranosyloxy)-11, 12- dihydroxy -2, 16- dioxo -, methyl ester. Cytotoxic test using MTT assay method showed that compound have IC<sub>50</sub> 9,7 µg/mL.</p>
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