Abstract
[RuCl (η6-p-cymene)(ligand 1)] (complex 1) was synthesized by simple mixing of 2-(1-((pyridine-2- yl)methyl)-1H-1,2,3-triazol-4-yl)ethyl sodium sulfate (ligand 1) with [RuCl2(η6-p-cymene)]2 in methanol. The microcrystals of the reported complex were characterized by FT-IR, 1H NMR, 13C NMR spectroscopic techniques and elemental analysis. The cytotoxic activity of the ruthenium complex wass tested against human cancer cells A375, A431, BxPC3, A549, HCT-15, LoVo cancer cell and human nontumor cell (human embryonic kidney HEK2) by the MTT assay method. The synthesized ruthenium complex exhibits a limited cytotoxic effect on human cancer cells and also reveals a dose-depended antimetastatic property against LoVo cancer cell.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
