Abstract
In this study, we used human umbilical vein endothelial cells (HUVEC) as an in vitro model to compare the cytotoxic activities of the venoms of two Macrovipera lebetina subspecies, M. l. obtusa from southern Anatolia and M. l. lebetina from northern Cyprus. Well-established 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide (MTT) assay was preferred to assess the cytotoxicity. Our results showed that venom reduced cell viability both in a time and dose-dependent manner. The cytotoxic effect of M. l. lebetina venom on HUVEC is reported for the first time in the present study.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
