Abstract
SUMMARY: Cold-sensitive mutants of bacteria are a source of strains defective in the assembly of ribosomes (Guthrie, Nashimoto & Nomura, 1969; Tai, Kessler & Ingraham, 1969). A study of cold-sensitive mutants in Aspergillus nidulans was undertaken in the hope that it would provide ribosomal mutants. Cold-sensitive (cs) mutants were isolated, and when crossed with wild-type the majority of 32 mutants tested segregated as single-gene mutations. One mutant, cs67, showed non-Mendelian segregation of its cold-sensitive character in such a cross. This paper presents further results demonstrating the extranuclear inheritance of CS67.
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