Abstract
A total of 2, 600 cytotrophoblastic cells from the molar tissue of 13 cases of non-invasive mole at the implantation site, and 1, 200 cytotrophoblastic cells from the molar tissue of 6 cases of invasive mole in the myometrium were studied cytomorphologically. Variation in size and shape of cytoplasma and nucleus, increased N/C ratio, granular chromatin pattern, multinucleation, and increased number of prominent nucleoli were characteristic of both groups. These characteristic morphologies are common with many other malignant cells in the current sense of cytodiagnosis.The leading papers so far published say that trophoblastic cells of non-invasive mole are easily distinguishable cytologically from those of invasive mole. To the contrary, our results led to the conclusion that the cytomorphological difference of cytotrophoblastic cells between non-invasive mole and invasive mole was rather quantitative than qualitative.Discussion is made on these results in relation to the nature of invasive mole.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: The Journal of the Japanese Society of Clinical Cytology
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
