Abstract
Abstract. Cytological specimens obtained by fine‐needle puncture from the liver of 3 patients with primary hepatic carcinoma and 12 patients with liver metastases of various tumours have been stained for the demonstration of naphthylamidase (N‐ase) and by the MGG method. The N‐ase staining method has earlier been shown to stain bile canaliculi in cytological liver preparations. In cases of primary hepatic carcinoma, bile canaliculi or canalicular fragments were recognisable among the tumour cells in preparations stained for N‐ase. In two cases of bile duct carcinoma the tumour cells showed a granular cytoplasmic reaction when stained for N‐ase. In the remaining cases the tumour cells were N‐ase‐negative. Consequently, staining for the demonstration of N‐ase seems quite helpful when interpreting cytological liver preparations from patients suffering from neoplastic disease of the liver.
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