Abstract

Acrylamide monomer has wide variety of applications which lead to its release into soils and water ways. The cytogenetic effects of acrylamide were investigated in roots of Allium cepa. The chemical exerted mitodepressive action on mitosis and induced a number of chromosomal changes and mitotic abnormalities. Chromosomal changes produced comprised of chromosome and chromatid breaks, fragmentation and stickiness in metaphase cells. Anaphase cells showed multipolar arrangement, unequal distribution, chromosomal bridges and micronucleated cells. Some of these effects appeared to be irreversible. The study suggests that continuous exposure to acrylamide may lead to genetic effects in plants and even higher organisms.

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