Abstract
Background. Breast lumps have varied pathology, and there are different techniques to prove the diagnosis. The aim of the present study is to analyze the role of fine needle aspiration cytology (FNAC) of the breast lesions at our center. Methods. We had retrospectively analysed 854 patients who underwent FNAC for primary breast lumps and 190 patients who underwent FNAC for an axillary lymph node in the year 2010. Results. Of 854 patients, histological correlation was available in 723 patients. The analysis was done for 812 patients as medical records were not available for 42 patients. FNAC was false negative in seven cases; 2 cases of phyllodes were reported as fibroadenoma, and 5 cases of carcinoma were diagnosed as atypical hyperplasia. The sensitivity, specificity, and false negative value of FNAC in diagnosing breast lumps were 99% (715/723), 100%, and 1%, respectively. Of 190 patients for whom FNAC was performed for axilla, 170 had proven to have axillary lymph node metastases, and the rest had reactive hyperplasia or inflammatory cells. Conclusions. FNAC is rapid, accurate, outpatient based, and less complicated procedure and helps in diagnosis of breast cancer, benign diseases, and axillary involvement in experienced hands with less chance of false results.
Highlights
Breast cancer is one of the most common cancers in women in India and is a leading cause for mortality and morbidity
The purpose of our study is to evaluate the efficacy of fine needle aspiration cytology (FNAC) in diagnosing breast lumps in our setting, and it is one of the largest studies reported in India [6]
A retrospective analysis of medical records of the patients with detected breast mass and Pathology Research International (a) palpable axillary lymph node who were evaluated by FNAC at our centre in the year 2010 was valuated
Summary
Breast cancer is one of the most common cancers in women in India and is a leading cause for mortality and morbidity. Breast tissue contains various tissue components, and there is change in composition of breast tissue with hormonal changes It has varied pathology, and there are various modalities to prove the diagnosis. FNAC can be done as an outpatient procedure and helps in rapid diagnosis. FNAC was false negative in seven cases; 2 cases of phyllodes were reported as fibroadenoma, and 5 cases of carcinoma were diagnosed as atypical hyperplasia. The sensitivity, specificity, and false negative value of FNAC in diagnosing breast lumps were 99% (715/723), 100%, and 1%, respectively. FNAC is rapid, accurate, outpatient based, and less complicated procedure and helps in diagnosis of breast cancer, benign diseases, and axillary involvement in experienced hands with less chance of false results
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